Update on Treatment and Prevention of Chronic Antibody Mediated Rejection in Renal Transplant Recipients

Yazarlar

  • Salman Tahir Shafi Sharif Medical and Dental College, Lahore

DOI:

https://doi.org/10.53778/pjkd40353

Anahtar Kelimeler:

Rejection, kidney transplant- acute rejection- chronic rejection- antibody mediated rejection- complement,- plasmapheresis- Bortezomib,- Rituximab- Eculizumab- Tocilizumab

Öz

Chronic antibody mediated rejection (AMR) is a major cause of allograft failure1,2. Chronic AMR clinically presents with proteinuria and gradual decline in renal function. The underlying mechanisms of AMR include both antibody mediated complement-dependent cytotoxicity, complement-independent cellular cytotoxicity and other mechanisms. The purpose of this review is to appraise recent literature on diagnosis, treatment and prevention of chronic AMR.

Yayınlanmış

2021-01-31

Nasıl Atıf Yapılır

Update on Treatment and Prevention of Chronic Antibody Mediated Rejection in Renal Transplant Recipients. (2021). Pakistan Journal of Kidney Diseases, 4(03). https://doi.org/10.53778/pjkd40353